Regenerative Medicine and the Thymus Gland

In the field of modern medicine, debilitating musculoskeletal injuries are becoming less of a threat to long-term vitality thanks to advancements in knowledge of the body’s own intrinsic recuperative mechanisms. Now, increasing awareness about the body’s own healing processes has revealed a vital but still poorly understood regenerative mechanism initiated by the thymus gland. While still undergoing extensive study, clinical research has revealed its function in physiological protection and regeneration. Proteins produced by the thymus gland play key roles in rehabilitation and recuperation from all types of musculoskeletal injury.

Thymus proteins are produced naturally by the thymus gland early in life, with most production ceasing before the onset of puberty. Also referred to as Tβ4, they exhibit a myriad of cellular functions that assist the repair and recovery of wounded tissue. These include the enhancement of new blood vessel formation (angiogenesis), cell migration, stem cell differentiation, and gene expression. When the body suffers a physical injury (for example, a torn quadriceps), these proteins are found in greater concentrations near the wounded area, where they facilitate healing through the aforementioned mechanisms. Clinical studies have shown them to consistently facilitate the healing and recovery of damaged bodily tissue.

For instance, a 1999 study published in the Journal of Investigative Dermatology found that the thymus gland accelerates wound healing through the process of angiogenesis. Researchers observed that treated subjects’ wounds contracted by a minimum of 11% more than control subjects’ wounds by the one week mark. Though the study was conducted on rats, the researchers concluded that the thymus gland was a wound healing factor with multiple activities.

Further, a 2014 study in the Journal of Orthopaedic Research showed that the thymus gland was able to enhance bone fracture healing in mice test subjects. The study found that treated mice had a 41% increase in peak force to failure and had up to 26% more new mineralized tissue than the control group. Importantly, researchers noted that the findings of their study indicated that thymus proteins played a key role in the healing of bone fractures.

Moreover, additional studies have demonstrated that thymus proteins have potent anti-inflammatory effects as well. A 1999 study published in Nature Medicine sought to explore the action mechanisms of Tβ4 as anti-inflammatory agents. After the study’s conclusion, researchers noted that the thymus may have far-reaching effects on the body’s inflammatory processes.

Certainly, research on the thymus gland’s healing mechanisms may have a beneficial impact on our knowledge of the body’s regenerative processes. Again, though still in the early phases, clinical study to this point has shown the thymus gland to be a key part of the body’s natural recuperative mechanisms. Currently, several research centers are invested in further clinical study to yield greater knowledge of the thymus gland.

To Be Better At Leading Change

70% of all change initiatives fail.

That’s a pretty startling statistic. Especially when you consider how important change is. I mean, we all acknowledge this, right? There aren’t many organizations out there saying, “You know what we need to do? We need to maintain the status quo, and we need to do it now!”

Every breakthrough involves change. Every innovation involves change. Every new product, policy, or service that moves you ahead of the competition involves change.

So change is vitally important-and yet 70% of change initiatives fail.

Why is that?

It’s because the people leading change don’t play the long game.

To put it another way, they declare victory too soon. Here’s why.

Change is difficult. There’s no getting around that. Change can be messy and uncertain-especially when you’re right in the middle of it. As Harvard professor and author of The Change Masters Rosabeth Moss Kanter puts it, “Everything can look like a failure in the middle.”

In fact, the middle part of change-the messy, uncertain part-can be so painful that we declare victory the instant we’re through it. It’s as if, as soon as we start to see light at the end of the tunnel, we wipe our brow, give each other a high five, and say, “Whew! That’s done!”

But it’s not done. Yes, you’ve made it through the messy part, but you haven’t anchored the change. It’s not yet a part of the culture. It hasn’t “stuck.”

You played the short game.

The truth is, change is a long game. The average successful corporate change initiative is a seven-year process-of which years three, four, and five are the messy part. But notice that there are still two years of anchoring left before the change sticks, before it becomes part of the culture.

It’s the part after the messy part that determines whether or not your change initiative will last.

So what, as a leader, do you do during this part?

You reinforce the change.

You actively look for any and every positive outcome that is a result of the change, and you become relentless about communicating these outcomes to the team. You have to be the one connecting the dots of success back to the change because, left to their own, your team members will not make the connection.

Only by reinforcing the change can you anchor the change, and only by anchoring the change can you make the change truly stick.

And once you do this, you’ll be in that exclusive club of leaders whose change initiatives succeed.

Social Networking in Apartment Complexes?

The Wall Street Journal itself is reporting a new trend in the world of apartment complexes. It seems that landlords have begun moving into the twentieth first century and are now using internet technology to create websites that are designed to meet the needs of renters who are increasingly comfortable doing everything from paying bills to choosing an apartment online. Through these sites they’re making it possible to pay your rent electronically as well as to see the actual view from an apartment unit for rent online. Apartment based social networking may be one of the most interesting developments of all, however.

Owner Benefits

Landlords see social networking tools in much the same way that a retailer with an online presence might. They create a community that is linked by an interest in a specific product-in this case a Dallas apartment complex-and generate a desired outcome as a result. For a retailer, it might be increased sales for their product. For an apartment complex though, it creates a community with ties to that complex. Members of that community are more likely to stay and even put down roots. For the landlord, this means a lower turnover rate and less time and money spent to fill units.

Resident Benefits

The social benefits for residents have the potential to be much greater, however. Knowing your neighbors by sight and having a casual relationship with them opens up a number of doors. Examples cited by the Wall Street Journal include a posting requesting a play date as well as one advertising for a dog sitter. As long as the social network is tightly confined to members of the physical community, so that potentially dangerous outsiders can’t snoop, it benefits that community by drawing it closer together. It’s just one of the benefits that a Dallas apartment can offer.

Different Applications Of An Industrial

An industrial oven is like a heated chamber that is used for a number of applications and also considered as thermal processing machines. A number of industries demand for the device and their need varies as per their application. Every single person when heard about the oven, so, they think of baking food in the kitchen, but, no it has many other applications other than just baking, which increases its demand in the market and especially in the industrial sectors. In case you are not aware of any of its applications, so, here we are to help you out. Read the article below and get to know about its wide applications that help you know a bit more about the device and its requirement in the different industries.

Here Are Some Common Application Of Industrial Ovens:

Powder Coating: Powder coating is important to create an extra layer of protection to the object and powder coating ovens are used for such coating, as it helps in heating to fuse into a layer when the desired temperature is reached.
Drying: The application of drying means removal of moisture from products before packing them, which ensure their long-life. And Drying Ovens are the ones that are designed for the same purpose and very helpful in removing the moisture.
Baking: Baking application here means the baking of the final products, which is performed by the industrial oven by incorporating the function of curing and drying as well. The device successfully performs this function because of its heated chamber that is meant to use for such purposes.
Curing: Another application for which an industrial oven used is curing. The device mainly coated the material to a specific temperature and holds it for a longer period.
Sterilizing: Last but not the least is sterilization. Yes, Industrial Ovens mainly the Hot Air ones are used for the purpose of sterilizing laboratory and surgical equipment like Scalpels, Spatula, Surgical Blades, and Glass Syringes, etc. The device uses dry heat to perform the process of sterilization.

Each of its application requires a specific amount of heat and different type of industrial oven and therefore, considering your application is important before investing in the device. To get a quality and feature-rich device, you should buy it from a reliable company that offers only the quality solutions. The device is available at reasonable price and offers you plenty of benefits and aids you attain your industry requirement.

Is Your Health Portfolio Balanced?

We are all aware of the need to balance our financial portfolio so that in times of hardship or when disaster strikes — stock market drops, pink slips, etc — we will be affected by financial challenges as little as possible. Having a substantial bank account allows us many opportunities that people with lesser financial savvy and preparation must for ego.

Perhaps you are at a “comfortable” financial level, able to pay off bills and credit cards timely, and have enough disposable income to enjoy a good quality of life. Perhaps you enjoy an “extremely high” financial level, with unending “toys”, travel when and where you want, and other opportunities for the “good life”. Either way you are able to handle sudden financial challenges and able to take advantage of financial opportunities as they come your way. Feels good, doesn’t it?

But what about your health portfolio? When faced with challenges such as a cold, flu season, children’s ear infections, etc. do you just accept them as part of life? What about when disaster strikes in the form of a serious health challenge to you or a family member. Is your health bank account equipped to fight back?

In the United States, the average age of disability (when quality of life becomes so poor that you need help for daily activities of living) is 65 years old. Modern medicine is providing miracles in keeping us alive longer — increasing our “lifespan”. But what about the quality of our lives? If we want to continue our “health span” along with our “lifespan”, it is imperative to raise the level of our health bank account as well as balance our health portfolio.

If you think the cost of health care has gone through the roof now, wait until the majority of baby boomers reach the “age of disability”. Now is the time to take a serious look at your own health bank account and ask “Do I have all the energy I need each day?”, “What is my ‘cushion’ in case of serious illness?” and “Does my health portfolio need balancing?”

Canada & Australia Immigration – Tips to Get Your PR Visa Faster

It is very obvious that when you want to settle in vibrant countries like Canada or Australia, you are keen to have your visa processed at a faster pace. In case of the temporary visas, you can do nothing but depend upon the employer to complete his job related formalities. But, when it comes to processing of permanent residency visas, the ball is always in your court. Permanent resident visas of these countries are issued considering the points applicant can score under respective immigration system. These points are often affected by time, age, work experience, education, spouse skills etc., and these factors eventually effect the success of the visa application. To ensure that your process is smooth and at a faster pace, here are three most important tips to be followed.

Tip No. 1: Apply at the right time-
It may seem astonishing to read but time is certainly a crucial factor in PR visa application. Under the time factor, application can be affected in the following manners:

  • Age: At the time of your application, if you are young you are more successful. This is because these countries have a high demand for professionals who are young (preferably 18yrs-25 yrs). Hence, to settle in Canada or Australia by getting yourself a higher preference and also great career prospects, apply when you are in your most demanded age range.
  • Peak Months: According to research, the best time to apply for Australia immigration is in the months of February and July. These two months are considered peak time for submitting Australia immigration. It is said that often applications during these peak months are associated with higher success results.
  • Intake Periods: Several provinces or States migration programs of each country have specific intake periods of PNP/State nomination applications. Keeping the nomination applications ready before these intake periods often results in quicker intake, improving chances for a quick visa.

Tip No. 2: Boost your CRS Score-
You may be aware of the fact that Canada & Australia have an immigration system that operates through a points based structure. Candidate’s eligibility as well as success for an international permanent residency status majorly depends on how well he can score under the points based system. If you believe that your score is hindering the success of your application, here are some ways by which you can improve your points.

    • Improve qualification: To improve your score, the best and easiest thing you can do is improve your qualification. If you a graduate, a higher degree will eventually increase your score and preferences for selection. Likewise, any certification or diploma that boosts your nominated occupations will also be a good step towards a score improvement.
    • Enhance work experience: Highest work experience candidates get good points under Canada and Australia’s points based system. If you have a chance to improve your work experience before your application or while your application is in process, go ahead, work hard and update. This may eventually increase your score and chances for a quicker visa.
    • Re-attempt IELTS: To become an international permanent resident, applicants must prove their proficiency level in the English language. For this IELTS is mandatory. As an applicant, if your IELTS score is what is delaying the process or getting you less score, re-attempt your IELTS. The best suggestion for improved results is to go for an expert help in preparation for IELTS.
    • Include Partner Skills: If your spouse or common law partner is accompanying your immigration, it is best to include his/her skills in the application, provided that she/he is eligible. This is because PR visa applicants are allotted with additional points for partner skills and this eventually increases points.

Try State/Province Nomination: If you meet the eligibility requirements of a respective State or Province, applying for a State Nomination increase will increase your points and also boost your chance for quick visa success.

Tip No. 3: Get Expert Assistance-
Despite all your efforts, if you are still unable to fetch those great points to buck-up your process, then you may missing something that only an expert eye can catch. Get in touch with your city’s best immigration experts and get counseled about the aspects that will help you in your application. Since immigration experts are up-to date and have hands on experience in processing thousands of visa cases, they will help you analyze the loopholes of your case (if any) and show you ways towards a quicker success.

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Ethical Dilemmas Doctors Have to Confront

The ethics and professionalism in medicine are of core importance when it comes to the role of the physician in his code of conduct.

With the great prestige and nobility in this profession comes the great responsibility in doctor’s hand, as they have to go through quandary in situations when it comes to cases like euthanasia, abortion, making a decision of who even makes it onto a waiting list for organ transplant, quick and life-changing decisions, psychological pressure from the loved ones of the patient, the patients family blame the doctors if the patient is unable to make during surgery, they should understand that death is imminent and the doctors do, whatever they can to save a life.

The doctor must explain the procedure to the patient and give him full information about the benefits, risks, positive and negative effects, leaving up to the patient to make the choice about undergoing the surgical procedure. The doctor should not perform the surgical intervention, only taking into consideration his personal gains and benefits. His first priority always has to be the patients’ health and to act in the best interest to protect the patient from any kind of harm. The doctor should be impartial when it comes to the selection of deserving cases and their needs, and on the basis of their degree of sickness.

The one of the most important and foremost ethical concern is taking an informed consent. Informed Consent is taken in advance from the patient, it is an agreement or a gesture to permit the doctor to have his medical history, undergo examination procedure, diagnosis, treatment, and intervention. The patient should be competent, well aware; mentally and emotionally stable. In some cases, the patient in spite, of his serious condition, refuse to agree with the intervention or surgical procedure, where then doctors have to make a decision for the welfare of the patient.

The information of the patient can only be breached if:

  1. himself asks the physician.
  2. In the case of children, the information is conveyed to the parents; as they are very
    young to handle their condition.
  3. There is a need of the help of the healthcare team in solving the case. Whether, the disclosure is for the criminal investigation of crime or harm to others, assault case, protecting the vulnerable; such as in child abuse case.
  4. For research purposes but only as anonymous and after taking consent from the patient.
  5. When it comes to public interests it may be breached when a patient has a highly contagious disease such as tuberculosis; the doctor has to inform the patients family so that precautionary measures can be taken. If the patient has a sexually transmitted disease, let’s say HIV which is a communicable disease, the doctor may disclose his disease to his partner in order to protect from the risk of getting the disease.
  6. State registries where officials keep track of cases like diabetes, cancer, HIV/AIDS, Alzheimer disease, Amyotrophic lateral sclerosis, and many other diseases.

It is the duty of the doctor to act in his best interest while dealing with a case, abide by the principles in common clinical situations, and work in the beneficence of the patient and do no harm in the treatment procedure.
The common ethical conundrums that doctors’ have to face in their course of profession:-

1- Euthanasia:

Euthanasia or physician-assisted suicide is considered as one of the supreme problems when it comes to ethics of patients treatment. The decision of euthanasia by the patient or his family is made in order to reduce the suffering of the patient in his terminal sickness. It can be voluntary or involuntary. When the patient makes a decision, it is voluntary. When the physician makes a decision it is involuntary. However, may it be voluntary or involuntary, it is unethical.

The World Medical Association issued the following declaration on euthanasia:-

“Euthanasia, that is the act of deliberately ending the life of a patient, even at his own request or at the request of his close relatives, is unethical. This does not prevent the physician from respecting the will of a patient to allow the natural process of death to follow its course in the terminal phase of sickness.”

2- Staying within their boundaries:

Doctors have to work long hours, off work, and even operate in odd hours in hospital settings and have to treat patients irrespective of their age, gender, and other attributes. They have to work in coordination with other staff members, the nurses, anesthesiologist, interns, assistants and many related members. Personal relationship or intimate relationship between the doctor and any other member like, his fellow, intern, other staff member is unethical and is prohibited. Patients often offer gifts to the doctors when their treatment intervention has been successful, or when the surgery goes well. It is quite fine, to accept those gifts as long as they are in the form of sweets or bouquet. The patient who brings gifts during the intervention may cause trouble, it may be the sign the patient needs more of the doctors’ attention. The physician should simply show reluctance to such presents and should not accept them by justifying that its’ against the ethics of their respective field.

3- Organ transplant:

Unfortunately, the availability of the transplant organs is far less, than their demand. Doctors have to make a tough decision here, that who will receive the next available organ and who will not, keeping in view the whole scenario, and what criteria is used for determining the donor. The surgeon should opt to give the transplant organ to the deserving patient on the list, on the basis of his health condition.

The physician should be approachable, equitable, able to communicate effectively and compassionately respecting the dignity of the patient regardless of his race, ethnicity, cast, choice of lifestyle. He should be dedicated to his profession, attenuate the pain of the patient by all means, preserving the health and enhancing the quality of life.

Talking To Your Doctor Tips

When you are sick, taking an active role in your health care will get you the best services. You can start by improving your personal relationship with your doctor. Furthermore, you should let your doctor know about your current and past health care. Especially, if you are allergic to some medications, your doctor should know about it. If you have any medicines you are currently taking, you should bring them with you. Don’t forget to bring vitamins, x-rays, medical records, test results with you to the appointment.

Sometimes your doctor may ask embarrassing questions. It is important that you tell your doctor the truth, even if you are embarrassed. Lying to your doctor can lead to serious potential health risks.

If you don’t understand something, you should ask. Some people are afraid to speak up. You doctor will assume that you understand everything, if you do not ask questions. You should write down the questions in a piece of paper, if you have questions before the appointment. If you need more time to talk to your doctor, you need to let them know. If your doctor is busy, a nurse or a physician assistant may be able to help you. If everyone is busy, you should schedule another appointment to answer your questions.

If you can not remember all instructions from your doctor, you should write down your instructions. Some people use a tape recorder. Your doctor may even have brochures or other education materials for you. Ask you doctor for his/her contact’s information.

Scottsdale Real Estate Schools

Phoenix has been experiencing a rapidly growing real estate market and the prices of properties here have soared in recent months. Investors are flocking to Phoenix to view listings, shortlist properties, negotiate prices and buy condos and luxury waterfront property. Golfers want to retire in Phoenix. Baby boomers are booking properties for spending their retirement days. This flurry of activity has motivated a number of people to seek careers as real estate brokers and agents. They are granted their licenses to work in the profession from various real estate schools.

One of the leading real estate schools in Phoenix, Scottsdale Real Estate School offers real estate courses online and on CD-ROM. It’s never been so convenient to pass your real estate exams and achieve a license. The real estate courses offered include: real estate license, sales associate and broker?s pre-license, post license continuing education, and prep courses for students to prepare for real estate exams and state exams. They offer fully accredited real estate courses that meet the license qualification and continuing education requirements for real estate professionals in Phoenix. These courses can be done from anywhere around the world. Scottsdale Real Estate School is open 24 hours a day, 7 days a week. They believe in serving the student around the clock to better meet their needs.

Scottsdale Real Estate School has introduced the most convenient way available to fulfill the professional license educational requirement. Their CD-ROM and online real estate classes allows the aspirant to begin courses at any time. Upon passing the online exams, they receive a certificate of completion and full course credits. Additionally they offer a new and exciting way to obtain the required real estate education credits. They noticed that many students simply don’t have the time or desire to attend a class. For them, an online training course has been created.

There are a few criteria that need to be fulfilled before applying for a real estate broker license. It is required for the applicant to be at least 18 years of age when applying for a real estate license. Additionally he may not have had a real estate license denied within one year, or revoked within two years immediately before applying. Scottsdale Real Estate School helps the applicants with the license procedure and makes it as easy as it can be.